As therapeutic antibodies continue to transform modern medicine, reliable pharmacokinetic (PK) analysis has become an essential component of antibody drug development. Accurate quantification of therapeutic antibodies in preclinical studies requires highly specific detection reagents that can distinguish human IgG from endogenous immunoglobulins in animal models, ensuring precise and reproducible PK data.
To address this need, AlpVHHs has developed its High-Specificity Anti-Human IgG Nanobodies, engineered specifically for PK applications. Leveraging AlpVHHs' proprietary yeast display platform, these nanobodies were selected through a highly stringent screening process to recognize human IgG exclusively, with no detectable cross-reactivity to cynomolgus monkey IgG.
Developed specifically for pharmacokinetic studies, the Anti-Human IgG-Fc PK, AlpHcAbs® Mouse Antibody delivers outstanding specificity and sensitivity for detecting therapeutic human IgG antibodies.
● Specifically recognizes the Fc region of human IgG.
● No cross-reactivity with cynomolgus monkey IgG, mouse IgG, or other commonly used preclinical species.
● High-affinity recognition of all human IgG subclasses (IgG1, IgG2, IgG3, and IgG4).
● Compatible with commonly engineered Fc variants used in therapeutic antibody development.
● Manufactured using recombinant expression technology.
● Excellent batch-to-batch consistency.
● Stable supply for long-term research and development projects.
Code | Description | Application |
023-311-001 | ELISA,WB,ICC/IF,FIow Cyt | |
023-311-004 | ELISA,WB ,FIow Cyt | |
023-311-005 | ELISA, WB | |
023-401-004 | Anti-Human lgG(Fcγ Fragment specific)AlpHcAbs® Goat antibody(Biotin) | ELISA |
023-404-004 | Anti-Human lgG(Fab Fragment specific)AlpHcAbs® Goat antibody(Biotin) | ELISA |
067-101-005 | ELISA | |
067-102-003 | IP.CHIP,MS,Purification | |
023-101-003 | IP,CHIP,MS,Purification |
AlpVHHs specializes in Custom VHH Discovery & Development, providing high-quality reagents for antibody drug research, bioanalysis, and diagnostic development.
Our recombinant antibodies are designed to deliver high specificity, excellent reproducibility, and reliable long-term supply, helping researchers accelerate antibody therapeutic development with confidence.
