Human CD7-PE CAR TEST Kit

Details and Advantages

Code: APK152

Specification:

Applications: Flow Cyt

Reactivity: Human CD7

Conjugate: PE

Advantages:

High lot-to-lot consistency

Product Description Manual MSDS FAQ Citations

Product Detail

Description:
Human CD7-PE CAR TEST Kit is designed for detecting antibody expression of CAR related cell specifically. Human CD7-PE CAR TEST Kit is recombinant human CD7 antigen fused to PE. Based on FCM and/or ELISA, CD7-PE CAR TEST Kit reacts with Anti-human CD7 antibody and their chimerism.

Protein Construction：Human CD7(Ala26-Pro180) conjugated to PE
Expression System：CHO
Purity: Recombinant Expression and Affinity purified
Conjugate: PE(Ex: 488nm, Em: 575nm)
Concentration: 0.2mg/ml
Formation: Liquid, 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose, 0.01% proclin300, 50% Glycerol
Storage: Store at 4°C(Avoid freeze / thaw cycles), protect from light

Background:
T-Cell Antigen CD7 is a single-pass type I membrane protein that that belongs to the the immunoglobulin superfamily. Human CD7 is synthesized as a 240 amino acid precursor that contains a 25 amino acid signal sequence and a 215 amino acid mature chain with a Ig-like (immunoglobulin-like) domain. CD7 is normally expressed on all T-lymphocytes, NK-cells, pre-B lymphocytes and pleuripotent hematopoietic stem cells. CD7 plays an essential role in T-cell interactions, T-cell/B-cell interaction during early lymphoid development, T- and NK-cell activation and cytokine production. CD7 has been shown to interact with PIK3R1and SECTM1. However, the function of the CD7 protein in the immune system is still largely unknown.

FAQ

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