Anti-CSF2, AlpHcAbs® Human antibody

Details and Advantages

Code: 300-588-001

Specification:

Applications: ELISA,Flow Cyt

Reactivity: Human

Conjugate: Unconjugated

Advantages:

High lot-to-lot consistency Increased sensitivity and higher affinity Animal-free production

Product Description Manual MSDS FAQ Citations

Product Detail

Description:
Anti-CSF2, AlpHcAbs® Human antibody is designed for detecting human CSF2 specifically. Based on ELISA and/or FCM, Anti-CSF2, AlpHcAbs® Human antibody reacts with human CSF2 specifically.

Immunogen: Recombinant human CSF2
Host: Alpaca pacous
Isotype: Human IgG1
Conjugate: Unconjugated
Specificity: Human CSF2
Purity: Recombinant Expression and Affinity purified
Concentration: 1mg/ml
Formation: Liquid, 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose, 0.01% proclin300, 50% Glycerol
Storage: Store at –20 °C, (Avoid freeze / thaw cycles)

Background:
The GM-CSF gene encodes for a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form of the protein exists as a homodimer in the extracellular space. This gene is located in a cluster of related genes at the chromosome region 5q31, which has been associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include interleukins 4, 5, and 13. The gene is involved in promoting tissue inflammation. Elevated levels of cytokines, including the one produced by this gene, have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome. Mice that lack this gene or its receptor have been shown to develop pulmonary alveolar proteinosis.

FAQ

Citations

Related Products

Anti-IL18, AlpHcAbs® Human antibody

Anti-CD154, AlpHcAbs® Human antibody

Anti-LOXL2, AlpHcAbs® Human antibody

Anti-KLB, AlpHcAbs® Human antibody

Anti-GFRA3, AlpHcAbs® Human antibody

Anti-ADAMTSL5, AlpHcAbs® Human antibody

Anti-L-Selectin, AlpHcAbs® Human antibody

Anti-ACVR1, AlpHcAbs® Human antibody