Anti-CX3CL1, AlpHcAbs® Human antibody

Details and Advantages

Code: 300-593-001

Specification:

Applications: ELISA,Flow Cyt

Reactivity: Human

Conjugate: Unconjugated

Advantages:

High lot-to-lot consistency Increased sensitivity and higher affinity Animal-free production

Product Description Manual MSDS FAQ Citations

Product Detail

Description:
Anti-CX3CL1, AlpHcAbs® Human antibody is designed for detecting human CX3CL1 specifically. Based on ELISA and/or FCM, Anti-CX3CL1, AlpHcAbs® Human antibody reacts with human CX3CL1 specifically.

Immunogen: Recombinant human CX3CL1
Host: Alpaca pacous
Isotype: Human IgG1
Conjugate: Unconjugated
Specificity: Human CX3CL1
Purity: Recombinant Expression and Affinity purified
Concentration: 1mg/ml
Formation: Liquid, 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose, 0.01% proclin300, 50% Glycerol
Storage: Store at –20 °C, (Avoid freeze / thaw cycles)

Background:
Chemokines are a family of proteins associated with the trafficking of leukocytes in immune surveillance and inflammatory cell recruitment. They are classified based on the positions of key cysteine residues. CX3CL1 is a CX3C chemokine known to induce adhesion and migration of leukocytes mediated by a membrane-bound and soluble form respectively. Recent experiments have shown that CX3CL1 can suppress the production of nitrous oxide, interleukin-6, and TNF-a in activated microglia and neuronal cells, suggesting that it may act as an intrinsic inhibitor against neurotoxicity by activated microglia. Its receptor, CX3CR1, also functions as a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by CX3CL1.

FAQ

Citations

Related Products

Anti-SLC34A2, AlpHcAbs® Human antibody

Anti-IL3RA, AlpHcAbs® Human antibody

Anti-CD40, AlpHcAbs® Human antibody

Anti-PTPRC, AlpHcAbs® Human antibody

Anti-VEGFR2, AlpHcAbs® Human antibody

Anti-VTCN1, AlpHcAbs® Human antibody

Anti-AMHR2, AlpHcAbs® Human antibody

Anti-ICOS, AlpHcAbs® Human antibody