Anti-LRRC15, AlpHcAbs® Human antibody
Code: 300-697-001
Specification:
Applications: ELISA,Flow Cyt
Reactivity: Human
Conjugate: Unconjugated
Advantages:
High lot-to-lot consistency Increased sensitivity and higher affinity Animal-free production
Product Detail
Product Detail
Description:
Anti-LRRC15, AlpHcAbs® Human antibody is designed for detecting human LRRC15 specifically. Based on ELISA and/or FCM, Anti-LRRC15, AlpHcAbs® Human antibody reacts with human LRRC15 specifically.
Immunogen: Recombinant human LRRC15
Host: Alpaca pacous
Isotype: Human IgG1
Conjugate: Unconjugated
Specificity: Human LRRC15
Purity: Recombinant Expression and Affinity purified
Concentration: 1mg/ml
Formation: Liquid, 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose, 0.01% proclin300, 50% Glycerol
Storage: Store at –20 °C, (Avoid freeze / thaw cycles)
Background:
Leucine-rich repeats (LRRs) are 20-29 amino acid motifs that mediate protein-protein interactions. The primary function of these motifs is to provide a versatile structural framework for the formation of these protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in genes encoding LRR-containing proteins. The leucine-rich repeat-containing protein 15 (LRRC15, also designated LIB) is a 581 amino acid protein that contains 15 LRR repeats and is involved in cell-cell and/or -extracellular matrix interactions. LRRC15 is frequently overexpressed in multiple tumor types, most notably breast carcinoma. It is also associated with the pathogenesis of Alzheimer's disease.
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