Anti-NOTCH3, AlpHcAbs® Human antibody

Details and Advantages

Code: 300-717-001

Specification:

Applications: ELISA,Flow Cyt

Reactivity: Human

Conjugate: Unconjugated

Advantages:

High lot-to-lot consistency Increased sensitivity and higher affinity Animal-free production

Product Description Manual MSDS FAQ Citations

Product Detail

Description:
Anti-NOTCH3, AlpHcAbs® Human antibody is designed for detecting human NOTCH3 specifically. Based on ELISA and/or FCM, Anti-NOTCH3, AlpHcAbs® Human antibody reacts with human NOTCH3 specifically.

Immunogen: Recombinant human NOTCH3
Host: Alpaca pacous
Isotype: Human IgG1
Conjugate: Unconjugated
Specificity: Human NOTCH3
Purity: Recombinant Expression and Affinity purified
Concentration: 1mg/ml
Formation: Liquid, 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose, 0.01% proclin300, 50% Glycerol
Storage: Store at –20 °C, (Avoid freeze / thaw cycles)

Background:

NOTCH3 is the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction (with its cell-bound ligands delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human. NOTCH3 functions as a receptor for membrane-bound ligands Jagged1, Jagged2, and Delta1 to regulate cell-fate determination. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).

FAQ

Citations

Related Products

Anti-ITGAV, AlpHcAbs® Human antibody

Anti-CD28, AlpHcAbs® Human antibody

Anti-RSPO3, AlpHcAbs® Human antibody

Anti-CD40, AlpHcAbs® Human antibody

Anti-TMEFF2, AlpHcAbs® Human antibody

Anti-PRLR, AlpHcAbs® Human antibody

Anti-HTRA1, AlpHcAbs® Human antibody

Anti-TNFSF14, AlpHcAbs® Human antibody