Anti-PDGFRA, AlpHcAbs® Human antibody

Anti-PDGFRA, AlpHcAbs® Human antibody
Anti-PDGFRA, AlpHcAbs® Human antibody

Details and Advantages

Code: 300-722-001

Specification:

Applications: ELISA,Flow Cyt

Reactivity: Human

Conjugate: Unconjugated

Advantages:

High lot-to-lot consistency Increased sensitivity and higher affinity Animal-free production

Product Detail

Product Detail

Description:
Anti-PDGFRA, AlpHcAbs® Human antibody is designed for detecting human PDGFRA specifically. Based on ELISA and/or FCM, Anti-PDGFRA, AlpHcAbs® Human antibody reacts with human PDGFRA specifically.

Immunogen: Recombinant human PDGFRA
Host: Alpaca pacous
Isotype: Human IgG1
Conjugate: Unconjugated
Specificity: Human PDGFRA
Purity: Recombinant Expression and Affinity purified
Concentration: 1mg/ml
Formation: Liquid, 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose, 0.01% proclin300, 50% Glycerol
Storage: Store at –20 °C, (Avoid freeze / thaw cycles)

Background:
PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.

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