VHH-Human IgG1(L234A, L235A, G237A) Fc Isotype Control
Code: 400-101-019
Specification: 1mg / 20mg
Applications: Isotype Control
Reactivity:
Conjugate: Unconjugated
Advantages:
High lot-to-lot consistency
Increased sensitivity and higher affinity
Animal-free production
Product Detail
Product Detail
Description:
VHH-Human IgG1(L234A, L235A, G237A) Fc Isotype Control is designed as a negative control in VHH-Human IgG1 antibody(with the mutation L234A, L235A, G237A) staining applications. VHH-Human IgG1(L234A, L235A, G237A) Fc Isotype Control has the same immunoglobulin class and subclass as the VHH-Human IgG1 antibody(with the mutation L234A, L235A, G237A) which is used in the experiment but lack affinity to the protein of interest. VHH-Human IgG1(L234A, L235A, G237A) Fc Isotype Control makes experiments credible.
Isotype: VHH-Human IgG1 Fc
Conjugate: Unconjugated
Specificity: HEL(hen egg-white lysozyme)
Purity: Human cell production, Recombinant Expression and Affinity purified, > 95%(HPLC)
Concentration: 1mg/ml
Endotoxin: < 0.2 EU/mg(LAL gel clotting)
Formation: Liquid, 10mM PBS (pH 7.5)
Storage: Store at –20 °C, (Avoid freeze / thaw cycles)
Background:
Antibodies bind to a specific protein or antigen, but sometimes an antibody can bind to other proteins or cellular components in a non-specific manner. Experimental controls are critical in determining if the antibodies used in your experiment have any off-target binding capabilities. Off-target or non-specific binding by antibodies lead to false positive results, making it difficult to determine background staining from antigen-specific staining. Therefore, it is important to always include experimental controls to ensure reliable results.
VHH are single-domain antibodies derived from the variable regions of heavy chain of Camelidae immunoglobulin. The size of VHH is extremely small(<15KDa) compared to other forms of antibody fragment, which significantly increase the permeability of VHH. Thus VHH is considered of great value for research, diagnostics and therapeutics.
Application Notes:
Negative control for VHH-Human IgG1 Fc antibody(with the mutation L234A, L235A, G237A)
Using at a dilution as the antibody which is used in the experiment.
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+86 138 8067 6215
Address:
Building 16, No.99 Haiwang Road, Wenjiang, Chengdu, China 611130
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SEC-HPLC
The purity of Isotype Control is more than 95% by SECand and the molecular weight of this protein is around 80kDa.
