Anti-Human IgA, AlpSdAbs® VHH(HRP)

Details and Advantages

Code: 023-109-005

Specification:

Applications: ELISA

Reactivity: Human IgA

Conjugate: HRP

Advantages:

High lot-to-lot consistency Increased sensitivity and higher affinity Animal-free production

Product Description Manual MSDS FAQ Citations

Product Detail

Description:
Anti-Human IgA, AlpSdAbs® VHH(HRP) is designed for detecting human IgA specifically. Anti-Human IgA, AlpSdAbs® VHH(HRP) is based on monovalent, recombinant single domain antibody to human IgA coupled to HRP. Based on immunoelectrophoresis and/or ELISA, Anti-Human IgA, AlpSdAbs® VHH(HRP) reacts with human IgA chain selectively, no reactivity with human IgG, IgE, IgM, IgD.

Immunogen: Human IgA
Host: Alpaca pacous
Isotype: VHH domain of alpaca IgG2b/2c
Conjugate: HRP
Specificity: Human IgA
Cross-Reactivity: Does not bind to human IgG, IgE, IgM, IgD
Purity: Recombinant Expression and Affinity purified
Concentration: 1mg/ml
Formation: Liquid, 10mM PBS(pH 7.5), 0.05% sucrose, 0.1% trehalose, 0.01% proclin300, 50% Glycerol
Storage: Store at –20 °C(Avoid freeze / thaw cycles), Stable for 12 months at -20°C

Background:
In mammals, antibodies are classified into five main classes or isotypes–IgA, IgD, IgE, IgG and IgM. They are classed according to the heavy chain they contain – alpha, delta, epsilon, gamma or mu respectively. IgA is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system.
VHH are single-domain antibodies derived from the variable regions of heavy chain of Camelidae immunoglobulin. The size of VHH is extremely small(<15KDa) compared to other forms of antibody fragment, which significantly increase the permeability of VHH. Thus VHH is considered of great value for research, diagnostics and therapeutics.