Anti-TfR1, AlpHcAbs® Human antibody

Details and Advantages

Code: 300-754-001

Specification:

Applications: ELISA,Flow Cyt

Reactivity: Human

Conjugate: Unconjugated

Advantages:

High lot-to-lot consistency Increased sensitivity and higher affinity Animal-free production

Product Description Manual MSDS FAQ Citations

Product Detail

Description:
Anti-TfR1, AlpHcAbs® Human antibody is designed for detecting human TfR1 specifically. Based on ELISA and/or FCM, Anti-TfR1, AlpHcAbs® Human antibody reacts with human TfR1 specifically.

Immunogen: Recombinant human TfR1
Host: Alpaca pacous
Isotype: Human IgG1
Conjugate: Unconjugated
Specificity: Human TfR1
Purity: Recombinant Expression and Affinity purified
Concentration: 1mg/ml
Formation: Liquid, 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose, 0.01% proclin300, 50% Glycerol
Storage: Store at –20 °C, (Avoid freeze / thaw cycles)

Background:
Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.

FAQ

Citations

Related Products

Anti-DLL3, AlpHcAbs® Human antibody

Anti-CD11, AlpHcAbs® Human antibody

Anti-EPCAM, AlpHcAbs® Human antibody

Anti-SLC1A5, AlpHcAbs® Human antibody

Anti-IL5RA, AlpHcAbs® Human antibody

Anti-SLC34A2, AlpHcAbs® Human antibody

Anti-MUC16, AlpHcAbs® Human antibody

Anti-NT5E, AlpHcAbs® Human antibody