Development of anti idiotypic antibodies

Anti-idiotype antibodies can specifically recognize and bind to the idiotype of the variable region of the antibody to be tested, and are widely used in the development of therapeutic antibody drugs. Due to the similarity between anti-idiotype antibodies and anti-drug antibodies (ADA), they can be used as an important reference for immunogenicity and neutralizing antibody research. In addition, in the pharmacokinetic (PK) and pharmacodynamic (PD) analysis of antibody drugs, anti-idiotype antibodies can be used to detect the content of antibody drugs in the blood (free, bound and total).

Three types of Anti-Idiotype Antibodies

Monoclonal Anti-Idiotype Antibody Development

Service Advantages of Anti-Idiotype Antibody Development

AlpVHHs offers a comprehensive antibody development platform and extensive experience to provide customized anti-idiotype antibody development solutions for clients worldwide. These antibodies are widely used in pharmacokinetics (PK) and immunogenicity (ADA) analysis of therapeutic antibodies.

We offer multiple strategies to overcome common challenges in anti-idiotype antibody development. Our full-service workflow includes antigen preparation, monoclonal and polyclonal anti-idiotype antibody generation, assay development, and kit production. Each anti-idiotype antibody development project is tailor-made based on downstream assay requirements, ensuring reliable support throughout your therapeutic antibody development process.